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Article

TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression.

Molecular and cellular biology - 1 Jan 2005

Weber Achim, Liu Juhong, Collins Irene, Levens David

Abstract excerpt

A continuous stream of activating and repressing signals is processed by the transcription complex paused at the promoter of the c-myc proto-oncogene. The general transcription factor IIH (TFIIH) is held at promoters prior to promoter escape and so is well situated to channel the input of activators and repressors to modulate c-myc expression. We have compared cells expressing only a mutated p89 (xeroderma...

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Source

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Identifiers

PMID: 15601838
DOI: 10.1128/MCB.25.1.147-161.2005
PMCID: PMC538784

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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