Article
The origins and uses of mouse outbred stocks.
Nature genetics - 1 Nov 2005
Chia Ruth, Achilli Francesca, Festing Michael F W, Fisher Elizabeth M C
Abstract excerpt
Outbred mouse stocks, often used in genetics, toxicology and pharmacology research, have been generated in rather haphazard ways. Understanding the characteristics of these stocks and their advantages and disadvantages is important for experimental design. In many studies these mice are used inappropriately, wasting animals' lives and resources on suboptimal experiments. Recently, however, researchers from the...
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