Article
Warning: the use of heterogeneous mice may seriously damage your research.
Neurobiology of aging - 1 Jan 2000
Festing M F
Abstract excerpt
Genetically heterogeneous (GH) mice and rats continue to be widely used in research even though the case for using isogenic strains has been argued repeatedly. The paper by Miller et al. in this issue appears to be the only one in the last 22 to attempt a scientific justification for the continued use of (a limited subset of) GH stocks. However, although they are to be commended for bravery, they fail to make...
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