Article
Evaluation of the effects of androgen receptor gene trinucleotide repeats and prostate-specific antigen gene polymorphisms on prostate cancer.
Genetics and molecular research : GMR - 18 May 2012
Alptekin D, Izmirli M, Bayazit Y, Luleyap H U, Yilmaz M B, Soyupak B, Erkoc M A, Tansug Z
Abstract excerpt
The number of trinucleotide repeats [CAG (coding for polyglutamine), GGC (coding for polyglycine)] in the first exon of the androgen receptor (AR) gene and prostate-specific antigen (PSA) gene androgen response element I A/G polymorphism are both related to prostate cancer prognosis. We investigated whether these genomic changes occur in the AR and PSA genes, which are usually found in individuals with...
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