Article
In vitro study of matrix metalloproteinase/tissue inhibitor of metalloproteinase production by mesenchymal stromal cells in response to inflammatory cytokines: the role of their migration in injured tissues.
Cytotherapy - 1 Jan 2009
Tondreau Tatiana, Meuleman Nathalie, Stamatopoulos Basile, De Bruyn Cecile, Delforge Alain, Dejeneffe Marielle, Martiat Philippe, Bron Dominique, Lagneaux Laurence
Abstract excerpt
BACKGROUND AIMS: The transmigratory capacity of bone marrow (BM) mesenchymal stromal cells (MSC) through the endothelial cell barrier into various tissues and their differentiation potential makes them ideal candidates for cell therapy. Nevertheless, the mechanisms and agents promoting their migration are not fully understood. We evaluated the effects of several inflammatory cytokines on the migration of BM MSC...
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