Article
The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs.
Proceedings of the National Academy of Sciences of the United States of America - 28 Dec 2004
Esclatine Audrey, Taddeo Brunella, Roizman Bernard
Abstract excerpt
The U(L)41 protein of herpes simplex virus 1 has been reported to mediate the degradation of both viral and cellular mRNAs. Extensive studies on beta-actin and some viral mRNAs were consonant with this conclusion. In earlier studies, we reported that the U(L)41-dependent degradation of cellular mRNAs up-regulated after infection was selective. One class of the up-regulated mRNAs, exemplified by the...
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