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Article

The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation.

Journal of virology - 1 Oct 1998

Hann L E, Cook W J, Uprichard S L, Knipe D M, Coen D M

Abstract excerpt

Herpes simplex virus specifies two sets of transcripts from the UL24 gene, short transcripts (e.g., 1.4 kb), processed at the UL24 poly(A) site, and long transcripts (e.g., 5.6 kb), processed at the UL26 poly(A) site. The 1.4- and 5.6-kb transcripts initiate from the same promoter but are expressed with early and late kinetics, respectively. Measurements of transcript levels following actinomycin D treatment of...

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Identifiers

PMID: 9733806
DOI: 10.1128/JVI.72.10.7709-7714.1998
PMCID: PMC110073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation.PMID 9733806Read ↗

Herpes simplex virus ICP27 regulates alternative pre-mRNA polyadenylation and splicing in a sequence-dependent mannerSemantic proximity Read ↗

Regulation of viral gene expression by the herpes simplex virus 1UL24 protein (HSV-1UL24 inhibits accumulation of viral transcripts).Semantic proximity Read ↗

The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infectionSemantic proximity Read ↗

Processing of alpha-globin and ICP0 mRNA in cells infected with herpes simplex virus type 1 ICP27 mutants.Semantic proximity Read ↗

The many roles of the regulatory protein ICP27 during herpes simplex virus infectionSemantic proximity Read ↗

Hidden regulation of herpes simplex virus 1 pre-mRNA splicing and polyadenylation by virally encoded immediate early gene ICP27Semantic proximity Read ↗

Aberrant RNA polymerase initiation and processivity on the genome of a herpes simplex virus 1 mutant lacking ICP27.Semantic proximity Read ↗

Long-Read Isoform Sequencing Reveals a Hidden Complexity of the Transcriptional Landscape of Herpes Simplex Virus Type 1Semantic proximity Read ↗

The herpes simplex virus ICP27 protein: a multifunctional post-transcriptional regulator of gene expressionSemantic proximity Read ↗

Identification of herpes simplex virus RNAs that interact specifically with regulatory protein ICP27 in vivo.Semantic proximity Read ↗

The Many Roles of the Highly Interactive HSV Protein ICP27, A Key Regulator of InfectionSemantic proximity Read ↗

Herpes Simplex Virus Proteins ICP27 and UL47 Associate with Polyadenylate-Binding Protein and Control Its Subcellular DistributionSemantic proximity Read ↗

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