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Article

Herpes simplex virus infection stabilizes cellular IEX-1 mRNA.

Journal of virology - 1 Apr 2005

Hsu Wei-Li, Saffran Holly A, Smiley James R

Abstract excerpt

Herpes simplex virus (HSV) virion host shutoff protein (vhs) destabilizes cellular and viral mRNAs. Previous work from several laboratories has indicated that vhs accelerates the turnover of most host mRNAs and provided evidence that at least some of these are degraded via endonucleolytic cleavage near regions of translational initiation followed by 5'-->3' decay. In contrast, several recent reports have argued...

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Identifiers

PMID: 15767410
DOI: 10.1128/JVI.79.7.4090-4098.2005
PMCID: PMC1061573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Herpes simplex virus infection stabilizes cellular IEX-1 mRNA.PMID 15767410Read ↗

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The herpes simplex virus host shutoff (vhs) RNase limits accumulation of double stranded RNA in infected cells: Evidence for accelerated decay of duplex RNASemantic proximity Read ↗

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