Article
Polymorphism in the nuclear factor kappa-B binding promoter region of cyclooxygenase-2 is associated with an increased risk of bladder cancer.
Cancer letters - 10 Jan 2005
Kang Sokbom, Kim Yong Beom, Kim Moon-Hong, Yoon Kyung-Sik, Kim Jae Weon, Park Noh Hyun, Song Yong Sang, Kang Daehee, Yoo Keun-Young, Kang Soon Beom, Lee Hyo Pyo
Abstract excerpt
Cyclooxygenase-2 (COX-2) expression is mediated by constitutive nuclear factor (NF)-kappaB. The aim of this study was to investigate the association between the germline alteration of the NF-kappaB binding site of COX-2 and the risk of developing various types of human cancers. Using PCR and DNA...
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