Article
Insertion/deletion polymorphism in the promoter region of NFKB1 gene increases susceptibility for superficial bladder cancer in Chinese.
DNA and cell biology - 1 Jan 2010
Tang Tielong, Cui Shu, Deng Xianzhong, Gong Zhiyong, Jiang Guo, Wang Pingxi, Liao Bo, Fei Zhonghai, Xian Shuyan, Zeng Denang, Li Jianyong
Abstract excerpt
Recently, a functional insertion/deletion polymorphism (-94 insertion/deletion ATTG) in the promoter of NFKB1 gene, which encodes the p50 subunit of nuclear factor-kappaB protein complex, was identified. The aim of this study was to explore the association between this polymorphism and bladder cancer in a Chinese population. The NFKB1 polymorphism was assessed in 207 patients with superficial transitional cell...
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