Article
Significant Association of Cyclo-oxygenase 2 Genotypes with Upper Tract Urothelial Cancer.
Anticancer research - 1 May 2015
Chang Wen-Shin, Liao Cheng-Hsi, Hsu Chin-Mu, Huang Chung-Yu, Fang Hsin-Yuan, Kao Pei-Yu, Tsai Chia-Wen, Wu Hsi-Chin, Hu Pei-Shin, Wang Tzu-Chia, Syu Yun-Ru, Shui Hao-Ai, Bau Da-Tian
Abstract excerpt
AIM: Reliable biomarkers are in urgent need for diagnosis, outcome prediction and treatment-effect monitoring for upper tract urothelial carcinomas (UTUC). Although up-regulation of cyclo-oxygenase 2 (COX2) is found in stroma and tumor cells in more than half of the patients with UTUC investigated, the genomic contribution of COX2 to UTUC has not been studied. The study aimed to evaluate the association of six...
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