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Article

Octapeptide repeat region and N-terminal half of hydrophobic region of prion protein (PrP) mediate PrP-dependent activation of superoxide dismutase.

Biochemical and biophysical research communications - 21 Jan 2005

Sakudo Akikazu, Lee Deug-chan, Nishimura Takuya, Li Shuming, Tsuji Shoutaro, Nakamura Toyoo, Matsumoto Yoshitsugu, Saeki Keiichi, Itohara Shigeyoshi, Ikuta Kazuyoshi, Onodera Takashi

Abstract excerpt

Cellular prion protein PrP(C) contains two evolutionarily conserved domains among mammals; viz., the octapeptide repeat region (OR; amino acid residue 51-90) and the hydrophobic region (HR; amino acid residue 112-145). Accumulating evidence indicates that PrP(C) acts as an inhibitor of apoptosis...

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Identifiers

PMID: 15596141
DOI: 10.1016/j.bbrc.2004.11.092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15596141-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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