Article
Prion neurotoxicity: insights from prion protein mutants.
Current issues in molecular biology - 1 Jan 2010
Solomon Isaac H, Schepker Jessie A, Harris David A
Abstract excerpt
The chemical nature of prions and the mechanism by which they propagate are now reasonably well understood. In contrast, much less is known about the identity of the toxic prion protein (PrP) species that are responsible for neuronal death, and the cellular pathways that these forms activate. In...
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