Article
Evidence for a novel rheumatoid arthritis susceptibility locus on chromosome 6p.
Arthritis and rheumatism - 1 Dec 2004
Brintnell William, Zeggini Eleftheria, Barton Anne, Thomson Wendy, Eyre Stephen, Hinks Anne, Silman Alan J, Worthington Jane
Abstract excerpt
OBJECTIVE: To investigate whether the large linkage peak on chromosome 6p harbors rheumatoid arthritis (RA) susceptibility loci in addition to the well-characterized HLA-DRB1 gene. METHODS: DNA samples obtained from 377 UK RA affected sibling pair (ASP) families, comprising test (181 ASPs) and replication (196 ASPs) cohorts, were used for linkage analysis. Three hundred eighty-four patients with RA derived from a...
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