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Article

Fluid shear stress induces beta-catenin signaling in osteoblasts.

Calcified tissue international - 1 Nov 2004

Norvell S M, Alvarez M, Bidwell J P, Pavalko F M

Abstract excerpt

beta-Catenin plays a dual role in cells: one at cell-cell junctions and one regulating gene transcription together with TCF (T-cell Factor) in the nucleus. Recently, a role for beta-catenin in osteoblast differentiation and gene expression has begun to be elucidated. Herein we investigated the effects of fluid shear stress (FSS) on beta-catenin signaling. FSS is a well-characterized anabolic stimulus for...

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PMID: 15592796
DOI: 10.1007/s00223-004-0213-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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