Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Steady and oscillatory fluid flows produce a similar osteogenic phenotype.

Calcified tissue international - 1 Mar 2011

Case N, Sen B, Thomas J A, Styner M, Xie Z, Jacobs C R, Rubin J

Abstract excerpt

Mechanical loading induces positive changes in the skeleton due to direct effects on bone cells, which may include regulation of transcription factors that support osteoblast differentiation and function. Flow effects on osteoblast transcription factors have generally been evaluated after short e...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Clocks
Share to Cell Culture Techniques
Share to Core Binding Factor Alpha 1 Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Fluid

Share to Gene Expression Regulation

Share to Osteoblasts

Share to Osteogenesis

Share to RANK Ligand

Source

Open in PubMed Open full text

Identifiers

PMID: 21165611
DOI: 10.1007/s00223-010-9448-y
PMCID: PMC3588160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21165611-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Steady and oscillatory fluid flows produce a similar osteogenic phenotype.PMID 21165611Read ↗

Fluid flow shear stress and tissue remodeling—an orthodontic perspective: evidence synthesis and differential gene expression network analysisSemantic proximity Read ↗

Fluid shear stress induces beta-catenin signaling in osteoblasts.Semantic proximity Read ↗

Orchestrating osteogenic differentiation of mesenchymal stem cells—identification of placental growth factor as a mechanosensitive gene with a pro-osteogenic roleSemantic proximity Read ↗

Changes in Extracellular Matrix Gene and Protein Expressions in Human Trabecular Meshwork Cells in Response to Mechanical Fluid Flow StimulationSemantic proximity Read ↗

Bioreactor Strategy in Bone Tissue Engineering: Pre-Culture and Osteogenic Differentiation Under Two Flow ConfigurationsSemantic proximity Read ↗

Pulsed electromagnetic fields affect phenotype and connexin 43 protein expression in MLO-Y4 osteocyte-like cells and ROS 17/2.8 osteoblast-like cells.Semantic proximity Read ↗

Biomechanical stimulation of osteoblast gene expression requires phosphorylation of the RUNX2 transcription factorSemantic proximity Read ↗

Fluid shear stress magnitude, duration, and total applied load regulate gene expression and nitric oxide production in primary calvarial osteoblast cultures.Semantic proximity Read ↗

Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces.Semantic proximity Read ↗

Tension force stress downregulates the expression of osteogenic markers and mineralization in embryonic stem cell-derived embryoid bodiesSemantic proximity Read ↗

The Lineage Specification of Mesenchymal Stem Cells Is Directed by the Rate of Fluid Shear Stress.Semantic proximity Read ↗

Effects of ultrasound on Transforming Growth Factor-beta genes in bone cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.