Article
The Candida albicans KRE9 gene is required for cell wall beta-1, 6-glucan synthesis and is essential for growth on glucose.
Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 1998
Lussier M, Sdicu A M, Shahinian S, Bussey H
Abstract excerpt
We have isolated CaKRE9, a gene from Candida albicans, that is a functional homologue of the Saccharomyces cerevisiae KRE9 gene involved in beta-1,6-glucan synthesis. Disruption of the CaKRE9 gene in C. albicans shows that CaKre9p is required for the synthesis or assembly of this fungal polymer....
Topics
- Amino Acid Sequence
- Candida albicans
- Cell Division
- Cell Wall
- Fungal Proteins
- Genes, Fungal
- Glucans
- Glucose
- Glycoproteins
- Molecular Sequence Data
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid
- Species Specificity
- Transformation, Genetic
- beta-Glucans