Article
Yeast KRE genes provide evidence for a pathway of cell wall beta-glucan assembly.
The Journal of cell biology - 1 May 1990
Boone C, Sommer S S, Hensel A, Bussey H
Abstract excerpt
The Saccharomyces cerevisiae KRE1 gene encodes a Ser/Thr-rich protein, that is directed into the yeast secretory pathway, where it is highly modified, probably through addition of O-linked mannose residues. Gene disruption of the KRE1 locus leads to a 40% reduced level of cell wall (1----6)-beta-glucan. Structural analysis of the (1----6)-beta-glucan fraction, isolated from a strain with a krel disruption...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Wall
- Cloning, Molecular
- Fungal Proteins
- Glucans
- Membrane Glycoproteins
- Microscopy, Electron
- Molecular Sequence Data
- Molecular Structure
- Mutation