Article
Yeast beta-glucan synthesis: KRE6 encodes a predicted type II membrane protein required for glucan synthesis in vivo and for glucan synthase activity in vitro.
Proceedings of the National Academy of Sciences of the United States of America - 15 Dec 1991
Roemer T, Bussey H
Abstract excerpt
The KRE6 gene product is required for synthesis of the major beta-glucans of the yeast cell wall, as mutations in this gene confer reduced levels of both the (1----6)- and (1----3)-beta-D-glucan polymers. Cloning and sequencing of KRE6 reveals a gene encoding a predicted 80-kDa protein with a cen...
Topics
- Alleles
- Amino Acid Sequence
- Cell Membrane
- Chromosome Deletion
- Cloning, Molecular
- Genes, Fungal
- Genomic Library
- Glucans
- Glucosyltransferases
- Membrane Proteins
- Molecular Sequence Data
- Mutagenesis, Insertional
- Plasmids
- Restriction Mapping
- Saccharomyces cerevisiae
- Schizosaccharomyces pombe Proteins