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Article

Maintenance and self-renewal of long-term reconstituting hematopoietic stem cells supported by amniotic fluid.

Stem cells and development - 1 Oct 2004

Barria Emily, Mikels Amanda, Haas Martin

Abstract excerpt

The maintenance and self-renewal of hematopoietic stem cells (HSC) in culture is a central focus of hematopoietic stem cell research. In vivo, the balance between HSC differentiation, apoptosis, and self-renewal is regulated at the endosteal surface niche in the bone marrow (BM). In feeder-free cultures, the fate of HSC is affected by growth factors/interleukins and serum, which affect the balance between...

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Identifiers

PMID: 15588512
DOI: 10.1089/scd.2004.13.548

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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