Article
Human and murine amniotic fluid c-Kit+Lin- cells display hematopoietic activity.
Blood - 23 Apr 2009
Ditadi Andrea, de Coppi Paolo, Picone Olivier, Gautreau Laetitia, Smati Rim, Six Emmanuelle, Bonhomme Delphine, Ezine Sophie, Frydman René, Cavazzana-Calvo Marina, André-Schmutz Isabelle
Abstract excerpt
We have isolated c-Kit(+)Lin(-) cells from both human and murine amniotic fluid (AF) and investigated their hematopoietic potential. In vitro, the c-Kit(+)Lin(-) population in both species displayed a multilineage hematopoietic potential, as demonstrated by the generation of erythroid, myeloid, and lymphoid cells. In vivo, cells belonging to all 3 hematopoietic lineages were found after primary and secondary...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.