Article
Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACP1 and sex.
Diabetes/metabolism research and reviews - 1 Jan 2000
Bottini N, Meloni G F, Lucarelli P, Amante A, Saccucci P, Gloria-Bottini F, Bottini E
Abstract excerpt
BACKGROUND: We have investigated the possible role of ACP1 (also known as cLMWPTP: cytosolic low molecular weight phosphotyrosine phosphatase), a highly polymorphic enzyme involved in signal transduction of T-cell receptor, insulin receptor and other growth factors in the relationship between maternal age at delivery and risk of type 1 diabetes in the offspring. METHODS: One hundred and eighty-nine consecutive...
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