Article
Does the relative risk for type 1 diabetes conferred by HLA-DQ, INS, and PTPN22 polymorphisms vary with maternal age, birth weight, or cesarean section?
Pediatric diabetes - 1 Mar 2011
Stene Lars C, Rønningen Kjersti S, Undlien Dag E, Joner Geir
Abstract excerpt
BACKGROUND AND OBJECTIVE: Maternal age at birth, birth weight, and cesarean section has been associated with a weak but significant increase in risk of type 1 diabetes. The objective was to assess whether the relative risk for type 1 diabetes conferred by established susceptibility loci human leukocyte antigen (HLA)-DQ, INS, and PTPN22 differed depending on these perinatal factors. METHODS: We employed a...
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