Article
Maternal cigarette smoking, metabolic enzyme polymorphism, and developmental events in the early stages of extrauterine life.
Human biology - 1 Apr 2004
Bottini N, Gloria-Bottini F, Magrini A, Stefanini L, Cosmi E, Bergamaschi A, Cosmi E V, Bottini E
Abstract excerpt
The recent observation that maternal ACP1 genotype has an interactive effect with smoking on intrauterine development prompted us to search for a possible interaction effect between smoking and ACP1 genotype on haptoglobin (Hp) development in the neonatal period. ACP1 is a highly polymorphic protein tyrosine phosphatase involved in signal transduction of several growth factor receptors. The enzyme is composed of...
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