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Article

GATA6-positive lung adenocarcinomas are associated with invasive mucinous adenocarcinoma morphology, hepatocyte nuclear factor 4α expression, and KRAS mutations.

Histopathology - 1 Jul 2018

Nakajima Naoki, Yoshizawa Akihiko, Nakajima Tomoyuki, Hirata Masahiro, Furuhata Ayako, Sumiyoshi Shinji, Rokutan-Kurata Mariyo, Sonobe Makoto, Menju Toshi, Miyamoto Ei, Chen-Yoshikawa Toyofumi F, Date Hiroshi, Haga Hironori

Abstract excerpt

AIMS: GATA6 is known to play a role in lung development. However, its role in the carcinogenesis of lung cancer is not well studied. The aim of this study was to analyse GATA6 expression in lung adenocarcinomas (LAs) by immunohistochemistry (IHC) in order to define its association with clinicopathological characteristics. METHODS AND RESULTS: IHC analysis of GATA6 was performed with tissue microarray slides...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29469192
DOI: 10.1111/his.13500

Genes

GATA6
KRAS
CDX2
MUC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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