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Factors Influencing the Titer and Infectivity of Lentiviral Vectors

1 Oct 2004

Abstract excerpt

Lentiviral vectors have undergone several generations of design improvement to enhance their biosafety and expression characteristics, and have been approved for use in human clinical studies. Most preclinical studies with these vectors have employed easily assayed marker genes for the purpose of determining vector titers and transduction efficiencies. Naturally, the adaptation of these vector systems to clinical...

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PMID: 15585113
DOI: 10.1089/hum.2004.15.976

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