Article
[Osteopontin, a multi-faceted molecule].
Medecine sciences : M/S - 1 Oct 2005
Chabas Dorothée
Abstract excerpt
Osteopontin (OPN) was initially isolated from bovine bone cortex, as a complex syalilated phospho-glyco-protein of around 60 kDa, with many postranslational modifications. It has been long considered a structural bone protein linking bone cells to the bone extracellular matrix (osteo : bone, pontin : bridge). It has been cloned for the first time in 1986. Since then, it was established that it is part of a...
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