Article
The serotonin 5-HT1B receptor gene and attention deficit hyperactivity disorder.
Molecular psychiatry - 1 Jan 2003
Quist J F, Barr C L, Schachar R, Roberts W, Malone M, Tannock R, Basile V S, Beitchman J, Kennedy J L
Abstract excerpt
Recent research has suggested that serotonin, in addition to dopamine, may be involved in the development of attention deficit hyperactivity disorder (ADHD). Serotonin regulates dopaminergic neurotransmission in some areas of the brain via several 5-HT receptors including 5-HT1B. Animal studies have suggested the involvement of the 5-HT1B receptors in locomotor behaviour. For these reasons, we hypothesized that...
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