Article
Association between the 5HT1B receptor gene (HTR1B) and the inattentive subtype of ADHD.
Biological psychiatry - 1 Mar 2006
Smoller Jordan W, Biederman Joseph, Arbeitman Lori, Doyle Alysa E, Fagerness Jes, Perlis Roy H, Sklar Pamela, Faraone Stephen V
Abstract excerpt
BACKGROUND: Preclinical and genetic studies have implicated the 5HT1B receptor gene (HTR1B) in attention-deficit/hyperactivity disorder (ADHD). Association with a single nucleotide polymorphism (SNP; G861C) has been observed, but more extensive linkage disequilibrium analyses have not been reported. METHODS: To examine haplotype structure, we genotyped 21 SNPs in and around the gene in 12 multigenerational CEPH...
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