Article
Family-based association study of the serotonin transporter promoter region polymorphism (5-HTTLPR) in attention deficit hyperactivity disorder.
American journal of medical genetics - 8 Jan 2001
Manor I, Eisenberg J, Tyano S, Sever Y, Cohen H, Ebstein R P, Kotler M
Abstract excerpt
Low serotonin activity has been associated in both animal and human studies with measures of impulsivity, aggression, and disinhibited behaviors. Recently, a common 44-bp deletion in the promoter region of the serotonin transporter (5-HTTLPR) that results in reduced transcription and lower transporter protein levels was described. Toward unraveling a possible role of the 5-HTTLPR polymorphism in childhood...
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