Article
Further evidence for the association between attention deficit/hyperactivity disorder and the serotonin receptor 1B gene.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Dec 2009
Guimarães Ana P, Schmitz Marcelo, Polanczyk Guilherme V, Zeni Cristian, Genro Julia, Roman Tatiana, Rohde Luis A, Hutz Mara H
Abstract excerpt
Several evidences suggested that the serotonin 5-HT1B receptor gene (HRT1B) might be involved in the susceptibility to attention deficit/hyperactivity disorder (ADHD). Prior studies reported excess transmissions of the HRT1B gene 861G allele to affected ADHD children and of a haplotype block containing this variant and two functional promoter SNPs to probands with ADHD-inattentive subtype. However, some...
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