Article
Family-based association study of the serotonin transporter gene polymorphisms in Korean ADHD trios.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Nov 2005
Kim Soo-Jeong, Badner Judith, Cheon Keun-Ah, Kim Boong-Nyun, Yoo Hee-Jeong, Kim Se-Joo, Cook Edwin, Leventhal Bennett L, Kim Young Shin
Abstract excerpt
The dopamine (DA) system has been implicated in attention deficit hyperactivity disorder (ADHD) based on pharmacologic evidence. Because of an interaction between the serotonin (5-HT) and DA systems, the serotonin transporter gene (SLC6A4) has been considered as a candidate ADHD susceptibility gene. Two common polymorphisms, 5-HTTLPR and the intron 2 VNTR, have been studied for association in ADHD, with both...
Topics
- Attention Deficit Disorder with Hyperactivity
- Child
- Female
- Gene Frequency
- Genotype
- Haplotypes
- Humans
- Introns
- Korea
- Linkage Disequilibrium