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Article

Performance at altitude and angiotensin I-converting enzyme genotype.

European journal of applied physiology - 1 Mar 2005

Tsianos G, Eleftheriou K I, Hawe E, Woolrich L, Watt M, Watt I, Peacock A, Montgomery H, Grant S

Abstract excerpt

The "insertion" (I) rather than "deletion" (D) variant of the human angiotensin-converting enzyme (ACE) gene is associated with both lower tissue ACE activity and elite performance at high altitude. We examined whether the onset of acute mountain sickness (AMS), and further performance on reaching the summit of Mt. Blanc are influenced by the ACE I/D polymorphism. Two hundred and eighty-four climbers (235 males,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15578201
DOI: 10.1007/s00421-004-1284-1

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Performance at altitude and angiotensin I-converting enzyme genotype.PMID 15578201Read ↗

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