Article
Angiotensin-converting enzyme genotype and the ventilatory response to exertional hypoxia.
The European respiratory journal - 1 Nov 2003
Patel S, Woods D R, Macleod N J, Brown A, Patel K R, Montgomery H E, Peacock A J
Abstract excerpt
The "insertion" (I) rather than "deletion" (D) variant of the human angiotensin-converting enzyme (ACE) gene is associated with both lower tissue ACE activity and elite performance at high altitude. Three genotypes, II, ID and DD, are thus represented in the population. The authors examined whether an improved ventilatory response to hypoxic exercise may contribute to this effect. Subjects (n=60; 37 male,...
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