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Article

Angiotensin-converting enzyme genotype and arterial oxygen saturation at high altitude in Peruvian Quechua.

High altitude medicine & biology - 1 Jan 2008

Bigham Abigail W, Kiyamu Melisa, León-Velarde Fabiola, Parra Esteban J, Rivera-Ch Maria, Shriver Mark D, Brutsaert Tom D

Abstract excerpt

The I-allele of the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism has been associated with performance benefits at high altitude (HA). In n = 142 young males and females of largely Quechua origins in Peru, we evaluated 3 specific hypotheses with regard to the HA benefits of the I-allele: (1) the I-allele is associated with higher arterial oxygen saturation (Sa(O(2))) at HA, (2)...

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Identifiers

PMID: 18578648
DOI: 10.1089/ham.2007.1066
PMCID: PMC3140306

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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