Article
Differences in the folding transition state of ubiquitin indicated by phi and psi analyses.
Proceedings of the National Academy of Sciences of the United States of America - 14 Dec 2004
Sosnick Tobin R, Dothager Robin S, Krantz Bryan A
Abstract excerpt
We compare the folding transition state (TS) of ubiquitin previously identified by using psi analysis to that determined by using analysis. Both methods attempt to identify interactions and their relative populations at the rate-limiting step for folding. The TS ensemble derived from psi analysis has an extensive native-like chain topology, with a four-stranded beta-sheet network and a portion of the major helix....
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