Article
The oxidative burst at fertilization is dependent upon activation of the dual oxidase Udx1.
Developmental cell - 1 Dec 2004
Wong Julian L, Créton Robbert, Wessel Gary M
Abstract excerpt
The sea urchin egg is a quiescent cell...until fertilization, when the egg is activated. The classic respiratory burst at fertilization is the result of prodigious hydrogen peroxide production, but the mechanism for this synthesis is not known. Here we quantitate the kinetics of hydrogen peroxide synthesis at a single-cell level using an imaging photon detector, showing that 60 nM hydrogen peroxide accumulates...
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