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Article

Genotyping SNPs using a UV-photocleavable oligonucleotide in MALDI-TOF MS.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005

Vallone Peter M, Fahr Kristina, Kostrzewa Markus

Abstract excerpt

Matrix-assisted laser desorption time-of-flight mass spectrometry coupled with allele-specific primer extension is a proven method for typing single nucleotide polymorphisms (SNPs). A novel modification upon this methodology is the incorporation of a photocleavable linker within the extension primer. After completion of the primer extension reaction, photocleavage of the extension products results in two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15570107
DOI: 10.1385/1-59259-867-6:169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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