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Article

Calcium regulation of growth and differentiation in Streptococcus pneumoniae.

Journal of general microbiology - 1 Jan 1992

Trombe M C, Clavé C, Manias J M

Abstract excerpt

Streptococcus pneumoniae requires 0.15 mM-Ca2+ in the medium for optimal growth. Increasing the Ca2+ concentration to 1 mM triggers either a differentiative state, competence for genetic transformation during exponential growth, or partial lysis as soon as the cultures enter stationary phase. Genetic and physiological data both suggest that these responses are under the control of activator(s), excreted in the...

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PMID: 1556558
DOI: 10.1099/00221287-138-1-77

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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