Article
Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases.
Molecular microbiology - 1 Aug 1997
Dintilhac A, Alloing G, Granadel C, Claverys J P
Abstract excerpt
The adcCBA putative operon of Streptococcus pneumoniae, an important human pathogen, was identified in a search for transformation-deficient mutants. It was found to exhibit homology to ATP-binding cassette (ABC) transport operons encoding streptococcal adhesins such as FimA of Streptococcus para...
Topics
- ATP-Binding Cassette Transporters
- Adhesins, Bacterial
- Bacterial Proteins
- Blotting, Northern
- Blotting, Western
- Carrier Proteins
- Lipoproteins
- Manganese
- Membrane Transport Proteins
- Metalloproteins
- Mutation
- RNA, Messenger
- Streptococcus pneumoniae
- Transformation, Genetic
- Virulence
- Zinc