Article
Characterization of a calcium porter of Streptococcus pneumoniae involved in calcium regulation of growth and competence.
Journal of general microbiology - 1 Mar 1993
Trombe M C
Abstract excerpt
It is shown that Streptococcus pneumoniae possesses a Ca2+ transporter, sensitive to the amiloride derivative 2',4'-dimethylbenzamil (DMB), which is essential for grown at high Ca(2+)-concentrations, and which mediates the triggering by Ca2+ of competence for genetic transformation in the exponential phase and autolysis in the late exponential phase. DMB inhibited both Ca2+ transport and the Ca2+ response....
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