Article
Pleiotropic mutations alter the kinetics of calcium transport, competence regulation, autolysis and experimental virulence in Streptococcus pneumoniae.
Research in microbiology - 1 Jan 1998
Azoulay-Dupuis E, Rieux V, Rivier C, Trombe M C
Abstract excerpt
Streptococcus pneumoniae is a pathogen in which the extracellular calcium concentration plays a major physiological role, in growth as well as in the induction of competence for genetic transformation and activation of autolysis. Both responses are under the control of a protein activator exporte...
Topics
- Animals
- Autolysis
- Bacteriolysis
- Biological Transport
- Calcium
- Enzymes
- Mice
- Mutation
- N-Acetylmuramoyl-L-alanine Amidase
- Pneumococcal Infections
- Streptococcus pneumoniae
- Transformation, Bacterial
- Virulence