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A programmed cell division delay preserves genome integrity during natural genetic transformation in Streptococcus pneumoniae

14 Nov 2017

Abstract excerpt

Competence for genetic transformation is a differentiation program during which exogenous DNA is imported into the cell and integrated into the chromosome. In Streptococcus pneumoniae, competence develops transiently and synchronously in all cells during exponential phase, and is accompanied by a pause in growth. Here, we reveal that this pause is linked to the cell cycle. At least two parallel pathways impair...

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PMID: 29158515
DOI: 10.1038/s41467-017-01716-9

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