Article
Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C).
Pharmacogenetics - 1 Nov 2004
Iwai Megumi, Suzuki Hiroshi, Ieiri Ichiro, Otsubo Kenji, Sugiyama Yuichi
Abstract excerpt
OBJECTIVE: Two kinds of single nucleotide polymorphism (SNP; Asn130Asp and Val174Ala) are frequently observed in the liver specific transporter, organic anion transporting polypeptide 1B1 (OATP1B1/OATP-C) gene. Although these two SNPs occur independently in European-Americans, Val174Ala is mostly...
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