Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A dominant role for CD8+-T-lymphocyte selection in simian immunodeficiency virus sequence variation.

Journal of virology - 1 Dec 2004

O'Connor David H, McDermott Adrian B, Krebs Kendall C, Dodds Elizabeth J, Miller Jacqueline E, Gonzalez Edna J, Jacoby Timothy J, Yant Levi, Piontkivska Helen, Pantophlet Ralph, Burton Dennis R, Rehrauer William M, Wilson Nancy, Hughes Austin L, Watkins David I

Abstract excerpt

CD8(+) T lymphocytes (CD8-TL) select viral escape variants in both human immunodeficiency virus and simian immunodeficiency virus (SIV) infections. The frequency of CD8-TL viral escape as well as the contribution of escape to overall virus diversification has not been assessed. We quantified CD8-...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD8-Positive T-Lymphocytes
Share to Epitopes, T-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Macaca mulatta

Share to Sequence Analysis, DNA

Share to Simian Acquired Immunodeficiency Syndrome

Share to Simian Immunodeficiency Virus

Share to Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 15564508
DOI: 10.1128/JVI.78.24.14012-14022.2004
PMCID: PMC533930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15564508-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A dominant role for CD8+-T-lymphocyte selection in simian immunodeficiency virus sequence variation.PMID 15564508Read ↗

Hierarchy of multiple viral CD8+ T-cell epitope mutations in sequential selection in simian immunodeficiency infection.Semantic proximity Read ↗

Selection on the human immunodeficiency virus type 1 proteome following primary infection.Semantic proximity Read ↗

Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope.Semantic proximity Read ↗

Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution.Semantic proximity Read ↗

Acute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus.Semantic proximity Read ↗

CD8+ T cell escape mutations in simian immunodeficiency virus SIVmac239 cause fitness defects in vivo, and many revert after transmission.Semantic proximity Read ↗

Maintenance of AP-2-Dependent Functional Activities of Nef Restricts Pathways of Immune Escape from CD8 T Lymphocyte Responses.Semantic proximity Read ↗

Immune-mediated positive selection drives human immunodeficiency virus type 1 molecular variation and predicts disease duration.Semantic proximity Read ↗

Estimating the effectiveness of simian immunodeficiency virus-specific CD8+ T cells from the dynamics of viral immune escape.Semantic proximity Read ↗

Variation in simian immunodeficiency virus env is confined to V1 and V4 during progression to simian AIDS.Semantic proximity Read ↗

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia.Semantic proximity Read ↗

Acute-phase CD4+ T cell responses targeting invariant viral regions are associated with control of live-attenuated simian immunodeficiency virusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.