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An oxidized low‐density lipoprotein receptor gene variant is inversely associated with the severity of coronary artery disease

1 Nov 2004

Abstract excerpt

BACKGROUND: A lectin-like oxidized low-density lipoprotein (LDL) receptor-1 (LOX-1) is the major receptor of oxidized LDL in endothelial cells. The expression of LOX-1 was shown to be upregulated in atherosclerotic lesions. Recently, LOX-1 gene polymorphism (G501C) was reported to be associated with myocardial infarction (MI). HYPOTHESIS: Our study was undertaken to elucidate the association between this...

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PMID: 15562935
DOI: 10.1002/clc.4960271112

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