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Article

Is LOX-1 K167N polymorphism protective for coronary artery disease?

In vivo (Athens, Greece) - 1 Jan 2000

Kurnaz Ozlem, Aydogan Hülya Yilmaz, Isbir C Selim, Tekeli Atike, Isbir Turgay

Abstract excerpt

BACKGROUND: Human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1, OLR1) has been identified as a cell surface endocytosis receptor for oxidized low-density lipoprotein (oxLDL) on vascular endothelial cells. OxLDLs are avidly ingested by macrophages, resulting in foam cell formation. OxLDLs are also involved in inducing smooth muscle cell migration, proliferation and transformation. A single...

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Share to Coronary Artery Disease
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Share to Molecular Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Restriction Fragment Length

Share to Polymorphism, Single Nucleotide

Share to Scavenger Receptors, Class E

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Source

Identifiers

PMID: 20023241

Genes

CAD
LOX
OLR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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