Article
Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction.
Biochemical and biophysical research communications - 28 Mar 2003
Tatsuguchi Mariko, Furutani Michiko, Hinagata Jun-ichi, Tanaka Takeshi, Furutani Yoshiyuki, Imamura Shin-ichiro, Kawana Masatoshi, Masaki Tomoh, Kasanuki Hiroshi, Sawamura Tatsuya, Matsuoka Rumiko
Abstract excerpt
Lectin-like oxidized low-density lipoprotein receptor (LOX-1/OLR1) has been suggested to play a role in the progression of atherogenesis. We analyzed the OLR1 gene and found a single nucleotide polymorphism (SNP), G501C, in patients with ischemic heart disease from a single family, which resulted in the missense mutation of K167N in LOX-1 protein. We compared the group of patients with myocardial infarction (MI)...
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