Article
[Significance of serum oxidative stress related markers and genotype of GST gene in the pathogeneses of primary biliary cirrhosis].
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology - 1 Oct 2004
Komuro Osamu, Takahashi Hiroki, Sato Kenichi, Tamaki Shigeo, Zeniya Mikio, Toda Gotaro
Abstract excerpt
The studies using an immunohistological technique revealed that overexpression of oxidative stress-related substance such as HNE was observed in the liver of primary biliary cirrhosis patients. These data suggested that oxidative stress participated in the pathogenesis of primary biliary cirrhosis. Therefore we analyzed serum oxdative stress marker (8-OHdG) and anti oxidative substances (Mn-SOD and TRX) to...
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