Article
[Genetic predisposition to development of toxic liver cirrhosis caused by alcohol].
Genetika - 1 May 2001
Spitsyn V A, Nafikova A Kh, Spitsyna N Kh, Afanas'eva I S
Abstract excerpt
Comprehensive analysis of the contribution of genetic factors into predisposition to alcoholic toxic cirrhosis (TC) was performed. The ABO, RH, HP, TF, GC, PI, ACP1, PGM1, ESD, GLO1, and GST1 genetic polymorphisms were compared in 34- to 59-year-old male TC patients and control donors of the same sex and age. The phenotypic frequencies in the TC group deviated from the theoretically expected values; the main...
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